A7V (p.Ala7Val) variant of PLK1 (P53350)
A7V (p.Ala7Val) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
A7V (p.Ala7Val) variant details
- p.Ala7Val
- gnomAD 16-23678952-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.13
- CADD 22.20
- PolyPhen-2 0.02
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available