A7T (p.Ala7Thr) variant of PLK1 (P53350)
A7T (p.Ala7Thr) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
A7T (p.Ala7Thr) variant details
- p.Ala7Thr
- gnomAD 16-23678951-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.10
- CADD 17.20
- PolyPhen-2 0.02
- SIFT 0.39
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available