A7S (p.Ala7Ser) variant of PLK1 (P53350)
A7S (p.Ala7Ser) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
A7S (p.Ala7Ser) variant details
- p.Ala7Ser
- TOPMed rs1021134870
- gnomAD rs1021134870
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.09
- CADD 15.30
- PolyPhen-2 0.01
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available