A37E (p.Ala37Glu) variant of PLK1 (P53350)
A37E (p.Ala37Glu) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A37E (p.Ala37Glu) variant details
- p.Ala37Glu
- TOPMed rs1959280009
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.16
- CADD 15.40
- PolyPhen-2 0.07
- SIFT 1.00
- Most common in the East Asian population (allele frequency 5.1e-05)
- Structural context available