A34L (p.Ala34Leu) variant of PLK1 (P53350)
A34L (p.Ala34Leu) in PLK1 (P53350) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
A34L (p.Ala34Leu) variant details
- p.Ala34Leu
- gnomAD 16-23679022-TCCGG
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.442
- CADD 32.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available