A33V (p.Ala33Val) variant of PLK1 (P53350)
A33V (p.Ala33Val) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
A33V (p.Ala33Val) variant details
- p.Ala33Val
- ExAC rs774608785
- TOPMed rs774608785
- gnomAD rs774608785
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.09
- CADD 18.90
- PolyPhen-2 0.18
- SIFT 0.15
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available