A33S (p.Ala33Ser) variant of PLK1 (P53350)
A33S (p.Ala33Ser) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A33S (p.Ala33Ser) variant details
- p.Ala33Ser
- gnomAD rs1959279291
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.04
- CADD 12.90
- PolyPhen-2 0.01
- SIFT 0.59
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available