A27V (p.Ala27Val) variant of PLK1 (P53350)
A27V (p.Ala27Val) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A27V (p.Ala27Val) variant details
- p.Ala27Val
- TOPMed rs1315465388
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.12
- CADD 9.50
- PolyPhen-2 0.03
- SIFT 0.16
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available