A26V (p.Ala26Val) variant of PLK1 (P53350)
A26V (p.Ala26Val) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
A26V (p.Ala26Val) variant details
- p.Ala26Val
- gnomAD 16-23679009-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.17
- CADD 20.40
- PolyPhen-2 0.03
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available