A20S (p.Ala20Ser) variant of PLK1 (P53350)
A20S (p.Ala20Ser) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
A20S (p.Ala20Ser) variant details
- p.Ala20Ser
- gnomAD 16-23678990-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.05
- CADD 18.80
- PolyPhen-2 0.01
- SIFT 0.22
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available