A15T (p.Ala15Thr) variant of PLK1 (P53350)
A15T (p.Ala15Thr) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A15T (p.Ala15Thr) variant details
- p.Ala15Thr
- ExAC rs753468980
- TOPMed rs753468980
- gnomAD rs753468980
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.14
- CADD 24.20
- PolyPhen-2 0.08
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available