Y71S (p.Tyr71Ser) variant of PLAU (P00749)
Y71S (p.Tyr71Ser) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
Y71S (p.Tyr71Ser) variant details
- p.Tyr71Ser
- gnomAD 10-73912942-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.40
- MetaLR 0.42
- MetaSVM -0.12
- CADD 23.40
- PolyPhen-2 0.38
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available