Y71H (p.Tyr71His) variant of PLAU (P00749)
Y71H (p.Tyr71His) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
Y71H (p.Tyr71His) variant details
- p.Tyr71His
- Ensembl rs2096127703
- Missense
- Variant Prioritization Score for Impact Estimate 0.594
- REVEL 0.56
- MetaLR 0.53
- MetaSVM 0.25
- CADD 29.30
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available