Y71C (p.Tyr71Cys) variant of PLAU (P00749)
Y71C (p.Tyr71Cys) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
Y71C (p.Tyr71Cys) variant details
- p.Tyr71Cys
- ExAC rs756485791
- TOPMed rs756485791
- gnomAD rs756485791
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.42
- MetaLR 0.53
- MetaSVM 0.25
- CADD 25.40
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available