T69P (p.Thr69Pro) variant of PLAU (P00749)
T69P (p.Thr69Pro) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
T69P (p.Thr69Pro) variant details
- p.Thr69Pro
- gnomAD 10-73912935-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.444
- REVEL 0.34
- MetaLR 0.32
- MetaSVM -0.45
- CADD 24.80
- PolyPhen-2 0.92
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available