T38K (p.Thr38Lys) variant of PLAU (P00749)
T38K (p.Thr38Lys) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
T38K (p.Thr38Lys) variant details
- p.Thr38Lys
- gnomAD 10-73912242-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.22
- MetaLR 0.37
- MetaSVM -0.71
- CADD 17.10
- PolyPhen-2 0.03
- SIFT 0.16
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available