S18Y (p.Ser18Tyr) variant of PLAU (P00749)
S18Y (p.Ser18Tyr) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
S18Y (p.Ser18Tyr) variant details
- p.Ser18Tyr
- gnomAD 10-73911608-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.30
- CADD 21.50
- PolyPhen-2 0.83
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available