R2T (p.Arg2Thr) variant of PLAU (P00749)
R2T (p.Arg2Thr) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
R2T (p.Arg2Thr) variant details
- p.Arg2Thr
- gnomAD rs1231073436
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.29
- MetaLR 0.55
- MetaSVM -0.20
- CADD 19.10
- PolyPhen-2 0.37
- SIFT 0.07
- Most common in the REMAINING population (allele frequency 5e-05)
- Structural context available