R2K (p.Arg2Lys) variant of PLAU (P00749)
R2K (p.Arg2Lys) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
R2K (p.Arg2Lys) variant details
- p.Arg2Lys
- gnomAD rs1231073436
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.16
- MetaLR 0.44
- MetaSVM -0.49
- CADD 12.10
- SIFT 0.85
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available