P28T (p.Pro28Thr) variant of PLAU (P00749)
P28T (p.Pro28Thr) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
P28T (p.Pro28Thr) variant details
- p.Pro28Thr
- TOPMed rs2096125587
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.22
- MetaLR 0.37
- MetaSVM -0.64
- CADD 33.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available