N22D (p.Asn22Asp) variant of PLAU (P00749)
N22D (p.Asn22Asp) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
N22D (p.Asn22Asp) variant details
- p.Asn22Asp
- gnomAD 10-73912047-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.16
- CADD 5.71
- PolyPhen-2 0.04
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available