L9R (p.Leu9Arg) variant of PLAU (P00749)
L9R (p.Leu9Arg) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
L9R (p.Leu9Arg) variant details
- p.Leu9Arg
- TOPMed rs1458009938
- gnomAD rs1458009938
- Missense
- Variant Prioritization Score for Impact Estimate 0.516
- REVEL 0.50
- MetaLR 0.68
- MetaSVM 0.14
- CADD 23.40
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available