L34I (p.Leu34Ile) variant of PLAU (P00749)
L34I (p.Leu34Ile) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
L34I (p.Leu34Ile) variant details
- p.Leu34Ile
- gnomAD 10-73912229-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.556
- REVEL 0.46
- CADD 25.60
- PolyPhen-2 0.85
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available