K68E (p.Lys68Glu) variant of PLAU (P00749)
K68E (p.Lys68Glu) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
K68E (p.Lys68Glu) variant details
- p.Lys68Glu
- ExAC rs753049435
- gnomAD rs753049435
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.01
- CADD 14.30
- PolyPhen-2 0.04
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available