G73R (p.Gly73Arg) variant of PLAU (P00749)
G73R (p.Gly73Arg) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
G73R (p.Gly73Arg) variant details
- p.Gly73Arg
- gnomAD rs1396039304
- Missense
- Variant Prioritization Score for Impact Estimate 0.628
- REVEL 0.52
- MetaLR 0.57
- MetaSVM 0.27
- CADD 29.80
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available