G59E (p.Gly59Glu) variant of PLAU (P00749)
G59E (p.Gly59Glu) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data, published literature, and structural context.
G59E (p.Gly59Glu) variant details
- p.Gly59Glu
- gnomAD 10-73912305-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.668
- REVEL 0.62
- MetaLR 0.55
- MetaSVM 0.26
- CADD 27.30
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available