E63K (p.Glu63Lys) variant of PLAU (P00749)
E63K (p.Glu63Lys) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
E63K (p.Glu63Lys) variant details
- p.Glu63Lys
- gnomAD 10-73912316-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.588
- REVEL 0.44
- MetaLR 0.54
- MetaSVM 0.23
- CADD 32.00
- PolyPhen-2 0.97
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available