D65Y (p.Asp65Tyr) variant of PLAU (P00749)
D65Y (p.Asp65Tyr) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
D65Y (p.Asp65Tyr) variant details
- p.Asp65Tyr
- gnomAD 10-73912322-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.587
- REVEL 0.46
- MetaLR 0.45
- MetaSVM -0.07
- CADD 35.00
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available