D65E (p.Asp65Glu) variant of PLAU (P00749)
D65E (p.Asp65Glu) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
D65E (p.Asp65Glu) variant details
- p.Asp65Glu
- TOPMed rs1172750674
- gnomAD rs1172750674
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.13
- MetaLR 0.13
- MetaSVM -0.98
- CADD 12.00
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available