C39R (p.Cys39Arg) variant of PLAU (P00749)
C39R (p.Cys39Arg) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
C39R (p.Cys39Arg) variant details
- p.Cys39Arg
- gnomAD 10-73912244-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.699
- REVEL 0.86
- MetaLR 0.16
- MetaSVM -0.78
- CADD 28.90
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available