C31Y (p.Cys31Tyr) variant of PLAU (P00749)
C31Y (p.Cys31Tyr) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
C31Y (p.Cys31Tyr) variant details
- p.Cys31Tyr
- TOPMed rs1448686624
- gnomAD rs1448686624
- Missense
- Variant Prioritization Score for Impact Estimate 0.687
- REVEL 0.67
- MetaLR 0.65
- MetaSVM -0.01
- CADD 27.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available