A6S (p.Ala6Ser) variant of PLAU (P00749)
A6S (p.Ala6Ser) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A6S (p.Ala6Ser) variant details
- p.Ala6Ser
- ExAC rs759037884
- gnomAD rs759037884
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.26
- MetaLR 0.39
- MetaSVM -0.70
- CADD 15.90
- PolyPhen-2 0.25
- SIFT 0.59
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available