A3P (p.Ala3Pro) variant of PLAU (P00749)
A3P (p.Ala3Pro) in PLAU (P00749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
A3P (p.Ala3Pro) variant details
- p.Ala3Pro
- gnomAD rs2096124087
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.32
- MetaLR 0.43
- MetaSVM -0.51
- CADD 11.60
- PolyPhen-2 0.28
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available