W56R (p.Trp56Arg) variant of PLAT (P00750)
W56R (p.Trp56Arg) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
W56R (p.Trp56Arg) variant details
- p.Trp56Arg
- cosmic curated COSV54275
- Missense
- Variant Prioritization Score for Impact Estimate 0.727
- REVEL 0.79
- CADD 25.80
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available