V66M (p.Val66Met) variant of PLAT (P00750)
V66M (p.Val66Met) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
V66M (p.Val66Met) variant details
- p.Val66Met
- cosmic curated COSV54277
- 1000Genomes rs549540182
- ExAC rs549540182
- gnomAD rs549540182
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.22
- CADD 22.50
- PolyPhen-2 0.83
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available