V39L (p.Val39Leu) variant of PLAT (P00750)
V39L (p.Val39Leu) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
V39L (p.Val39Leu) variant details
- p.Val39Leu
- TOPMed rs1446229320
- Missense
- Variant Prioritization Score for Impact Estimate 0.521
- REVEL 0.41
- CADD 34.00
- PolyPhen-2 0.16
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available