V20L (p.Val20Leu) variant of PLAT (P00750)
V20L (p.Val20Leu) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
V20L (p.Val20Leu) variant details
- p.Val20Leu
- ExAC rs753589968
- TOPMed rs753589968
- gnomAD rs753589968
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.41
- CADD 0.63
- PolyPhen-2 0.01
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available