T138M (p.Thr138Met) variant of PLAT (P00750)
T138M (p.Thr138Met) in PLAT (P00750) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
T138M (p.Thr138Met) variant details
- p.Thr138Met
- rs759282035
- NCI-TCGA Cosmic COSV9953
- cosmic curated COSV99535
- ExAC rs759282035
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.407
- REVEL 0.27
- CADD 17.10
- PolyPhen-2 0.21
- SIFT 0.07
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available