T126K (p.Thr126Lys) variant of PLAT (P00750)
T126K (p.Thr126Lys) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
T126K (p.Thr126Lys) variant details
- p.Thr126Lys
- ExAC rs747219199
- gnomAD rs747219199
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.12
- CADD 7.80
- PolyPhen-2 0.02
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available