S134T (p.Ser134Thr) variant of PLAT (P00750)
S134T (p.Ser134Thr) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
S134T (p.Ser134Thr) variant details
- p.Ser134Thr
- ExAC rs752282051
- gnomAD rs752282051
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- REVEL 0.13
- CADD 7.82
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available