R62K (p.Arg62Lys) variant of PLAT (P00750)
R62K (p.Arg62Lys) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
R62K (p.Arg62Lys) variant details
- p.Arg62Lys
- cosmic curated COSV54274
- Missense
- Variant Prioritization Score for Impact Estimate 0.455
- REVEL 0.29
- CADD 16.30
- PolyPhen-2 0.21
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available