R58S (p.Arg58Ser) variant of PLAT (P00750)
R58S (p.Arg58Ser) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
R58S (p.Arg58Ser) variant details
- p.Arg58Ser
- ExAC rs767004270
- TOPMed rs767004270
- gnomAD rs767004270
- Missense
- Variant Prioritization Score for Impact Estimate 0.589
- REVEL 0.53
- CADD 24.90
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available