R124T (p.Arg124Thr) variant of PLAT (P00750)
R124T (p.Arg124Thr) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R124T (p.Arg124Thr) variant details
- p.Arg124Thr
- ExAC rs768663768
- TOPMed rs768663768
- gnomAD rs768663768
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.09
- CADD 0.84
- PolyPhen-2 0.00
- SIFT 0.62
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available