P59S (p.Pro59Ser) variant of PLAT (P00750)
P59S (p.Pro59Ser) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
P59S (p.Pro59Ser) variant details
- p.Pro59Ser
- ExAC rs762501048
- gnomAD rs762501048
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- REVEL 0.32
- CADD 24.00
- PolyPhen-2 0.98
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available