P59L (p.Pro59Leu) variant of PLAT (P00750)
P59L (p.Pro59Leu) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
P59L (p.Pro59Leu) variant details
- p.Pro59Leu
- TOPMed rs1587936145
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.18
- CADD 24.30
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available