G33R (p.Gly33Arg) variant of PLAT (P00750)
G33R (p.Gly33Arg) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
G33R (p.Gly33Arg) variant details
- p.Gly33Arg
- ExAC rs781130644
- TOPMed rs781130644
- gnomAD rs781130644
- Missense
- Variant Prioritization Score for Impact Estimate 0.661
- REVEL 0.70
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.10
- Most common in the HGDP:BALOCHI population (allele frequency 0.022)
- Structural context available