D105E (p.Asp105Glu) variant of PLAT (P00750)
D105E (p.Asp105Glu) in PLAT (P00750) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
D105E (p.Asp105Glu) variant details
- p.Asp105Glu
- gnomAD rs1805549123
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.33
- CADD 8.56
- PolyPhen-2 0.09
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available