T22S (p.Thr22Ser) variant of PINK1 (Q9BXM7)
T22S (p.Thr22Ser) in PINK1 (Q9BXM7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
T22S (p.Thr22Ser) variant details
- p.Thr22Ser
- gnomAD 1-20633612-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.08
- CADD 13.30
- PolyPhen-2 0.00
- SIFT 0.66
- Population evidence available
- Structural context available
- Literature evidence available