G35D (p.Gly35Asp) variant of PINK1 (Q9BXM7)
G35D (p.Gly35Asp) in PINK1 (Q9BXM7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
G35D (p.Gly35Asp) variant details
- p.Gly35Asp
- Ensembl rs2053015724
- Missense
- Variant Prioritization Score for Impact Estimate 0.491
- REVEL 0.45
- CADD 22.80
- PolyPhen-2 0.84
- SIFT 0.14
- Population evidence available
- Structural context available