Y53S (p.Tyr53Ser) variant of PIM1 (P11309)
Y53S (p.Tyr53Ser) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
Y53S (p.Tyr53Ser) variant details
- p.Tyr53Ser
- gnomAD 6-37170848-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.35
- CADD 27.40
- PolyPhen-2 0.77
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available